Rebellion is the fourth book in The 100 series, set a month after the arrival of additional colonists on Earth. The story follows Clarke, Bellamy, Glass, and Wells as they confront a new threat from a fanatical group known as "The Protectors." This cult believes in "healing" the planet by eliminating others and begins abducting members of the community.
Clarke and Bellamy's differing approaches to rescuing their friends—Clarke advocating for diplomacy and Bellamy for direct action—strain their relationship. Meanwhile, Glass, Octavia, and Wells are subjected to the cult's brainwashing tactics.
As the narrative unfolds, themes of leadership, trust, and the complexities of rebuilding society emerge. The characters must navigate these challenges to protect their community and secure a future on the planet they now call home.